1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 12
1.2 List of Figures 23
2 Introduction 24
2.1 Respiratory Devices Overview 24
3 Products under Development 27
3.1 Respiratory Devices - Pipeline Products by Stage of Development 27
3.2 Respiratory Devices - Pipeline Products by Segment 28
3.3 Respiratory Devices - Pipeline Products by Territory 29
3.4 Respiratory Devices - Pipeline Products by Regulatory Path 30
3.5 Respiratory Devices - Pipeline Products by Estimated Approval Date 31
3.6 Respiratory Devices - Ongoing Clinical Trials 32
4 Respiratory Devices - Pipeline Products under Development by Companies 33
4.1 Respiratory Devices Companies - Pipeline Products by Stage of Development 33
4.2 Respiratory Devices - Pipeline Products by Stage of Development 37
5 Respiratory Devices Companies and Product Overview 42
5.1 Ablynx NV Company Overview 42
5.2 Advanced Circulatory Systems Inc Company Overview 44
5.3 AerovectRx Corporation Company Overview 45
5.4 Afalapi Company Overview 46
5.5 AFT Pharmaceuticals Ltd Company Overview 47
5.6 Airing LLC Company Overview 48
5.7 Alaxo GmbH Company Overview 49
5.8 Aloro Medical AB Company Overview 52
5.9 ALung Technologies Inc Company Overview 53
5.10 Baby's Breath Ltd. Company Overview 58
5.11 Beijing Dehaier Medical Technology Co Ltd Company Overview 59
5.12 Blucore Pty Ltd Company Overview 63
5.13 Breethe, Inc. Company Overview 64
5.14 Broncus Medical Inc Company Overview 65
5.15 Capnia Inc Company Overview 66
5.16 Case Western Reserve University Company Overview 68
5.17 Circadiance LLC Company Overview 69
5.18 Cleveland Medical Devices Inc Company Overview 70
5.19 Coeo Labs Pvt Ltd Company Overview 71
5.20 Columbia Life Systems, Inc. Company Overview 73
5.21 Creare Inc. Company Overview 74
5.22 CSA Medical Inc Company Overview 75
5.23 Deca-Medics Inc Company Overview 77
5.24 DesignWise Medical Inc. Company Overview 78
5.25 Discover Medical Device Ltd. Company Overview 80
5.26 Endoclear LLC Company Overview 82
5.27 Filtara, Inc. Company Overview 83
5.28 Fisher & Paykel Healthcare Corporation Limited Company Overview 84
5.29 GE Healthcare Ltd Company Overview 86
5.30 GeNO LLC Company Overview 87
5.31 Hadassah Medical Center Company Overview 88
5.32 Haemair Ltd Company Overview 89
5.33 Hamilton Medical AG Company Overview 90
5.34 HCi Viocare Technologies Ltd Company Overview 91
5.35 Holaira Inc Company Overview 92
5.36 Innovent Medical Solutions Ltd Company Overview 95
5.37 IntelliBreathe Ltd. Company Overview 98
5.38 iSonea (Israel) Limited Company Overview 99
5.39 John Hopkins University Company Overview 105
5.40 Lehigh University Company Overview 107
5.41 Liberate Medical, LLC Company Overview 108
5.42 LifeServe Innovations, LLC Company Overview 111
5.43 Lingua Flex LLC Company Overview 113
5.44 Lungpacer Medical Inc Company Overview 114
5.45 Marquette University Company Overview 115
5.46 Massachusetts Institute of Technology Company Overview 116
5.47 McGowan Institute for Regenerative Medicine Company Overview 117
5.48 MedArray Inc. Company Overview 120
5.49 Medical Developments International Ltd Company Overview 121
5.50 Medivations Pty Ltd Company Overview 123
5.51 Mergenet Medical, Inc. Company Overview 124
5.52 Merit Medical Systems, Inc. Company Overview 125
5.53 Metamason Inc Company Overview 127
5.54 Michigan Critical Care Consultants, Inc. Company Overview 129
5.55 Miromatrix Medical Inc Company Overview 131
5.56 mPhase Technologies, Inc. Company Overview 132
5.57 Nanyang Technological University Company Overview 134
5.58 Neonatal Rescue LLC Company Overview 136
5.59 New Air, Inc. Company Overview 137
5.60 NightBalance BV Company Overview 138
5.61 Ninox Medical Ltd. Company Overview 140
5.62 Noveko International Inc Company Overview 141
5.63 Nu-Med Plus, Inc. Company Overview 143
5.64 Olympus Medical Systems Corp Company Overview 145
5.65 OneBreath Inc. Company Overview 149
5.66 Parion Sciences Inc Company Overview 150
5.67 Pavad Medical Company Overview 151
5.68 Pharmagenix AG Company Overview 152
5.69 Philips Healthcare Company Overview 153
5.70 Pneumedicare Ltd. Company Overview 155
5.71 Portaero Company Overview 156
5.72 Pulmonx Corp Company Overview 157
5.73 Reactive Innovations, LLC Company Overview 164
5.74 Respicardia Inc Company Overview 166
5.75 RespiNova Ltd Company Overview 168
5.76 Respiratory Research Inc Company Overview 169
5.77 Rhinomed Limited Company Overview 171
5.78 Rice University Company Overview 173
5.79 Sensory Innovation Solutions Company Overview 174
5.80 Sleep Secure LLC Company Overview 175
5.81 SleepUp Ltd Company Overview 176
5.82 Smart Oxygen Solutions, Inc. Company Overview 178
5.83 SolAeroMed Inc Company Overview 179
5.84 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 180
5.85 Stanford University Company Overview 181
5.86 Stirling Pharma Inc Company Overview 184
5.87 Tda Research Inc. Company Overview 185
5.88 Tenax Therapeutics Inc Company Overview 186
5.89 The Charles Stark Draper Laboratory Inc Company Overview 187
5.90 The Pennsylvania State University Company Overview 189
5.91 The University of Melbourne Company Overview 190
5.92 TigerLAB Company Overview 191
5.93 United Hayek Industries Inc. Company Overview 192
5.94 Universitatsklinikum Freiburg Company Overview 193
5.95 University of California Davis Company Overview 194
5.96 University of California Los Angeles Company Overview 195
5.97 University of California San Diego Company Overview 198
5.98 University of California San Francisco Company Overview 200
5.99 University of Illinois at Chicago Company Overview 203
5.100 University of Kansas Company Overview 204
5.101 University of Michigan Pediatric Device Consortium Company Overview 206
5.102 University of Missouri Company Overview 210
5.103 University of Pittsburgh Company Overview 211
5.104 University of Rochester Company Overview 212
5.105 University of Texas Medical Branch at Galveston Company Overview 213
5.106 Vivonics, Inc. Company Overview 214
5.107 Windmill Health Technologies Private Limited Company Overview 215
5.108 Wyngate Medical Technologies, Inc. Company Overview 216
5.109 Xenios AG Company Overview 217
5.110 Xo Thermix Medical, Inc Company Overview 219
5.111 Z-Cube Srl Company Overview 220
6 Respiratory Devices- Recent Developments 221
6.1 Dec 09, 2016: Adherium’s Smartinhaler Technology Chosen for Major Asthma Initiative 221
6.2 Dec 06, 2016: Inogen appoints new president and CEO 222
6.3 Dec 05, 2016: Another successful audit for local manufacturer, Bedfont Scientific 223
6.4 Nov 30, 2016: Ablynx Achieves First Milestone As Part Of Collaboration With Novo Nordisk 223
6.5 Nov 29, 2016: Cipla appoints Ireena Vittal as an Independent Director on its Board 223
6.6 Nov 28, 2016: Smith Medical’s Drug-Free Acapella Choice Vibratory PEP Therapy System Shown to Reduce Hospital Length of Stay by 1 1/2 Days for Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease 224
6.7 Nov 28, 2016: Invacare Appoints Susan Alexander to Board of Directors 225
6.8 Nov 23, 2016: Ablynx Announces Results For The First Nine Months Of 2016 And A Year-To-Date Business Update 225
6.9 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 227
6.10 Nov 22, 2016: Record Half Year Result for Fisher & Paykel Healthcare, Earnings Guidance Upgraded 230
6.11 Nov 22, 2016: BioLineRx Reports Third Quarter 2016 Financial Results 231
6.12 Nov 18, 2016: New GOLD Treatment Recommendations for Chronic Obstructive Pulmonary Disease Include Use of Endobronchial Valves to Treat Emphysema Patients 233
6.13 Nov 18, 2016: Dehaier Medical Changed its Name to Lianluo Smart 233
6.14 Nov 17, 2016: Independent Clinical Study Shows Adherium’s Smartinhaler Dramatically Improves Clinical Outcomes and Medication Adherence in Children with Asthma 234
6.15 Nov 16, 2016: CSA Medical Commences Phase B of the RejuvenAir System Safety and Feasibility Study For the Treatment of Chronic Bronchitis Patients 235
6.16 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 236
6.17 Nov 16, 2016: Kentucky Startups Join MassCONNECT Program Medical device entrepreneurs connect with MA innovation ecosystem through Kentucky—Massachusetts Turnpike 236
6.18 Nov 15, 2016: Henry Ford Radiation Oncology Receives 3-Year ACR Accreditation 237
6.19 Nov 15, 2016: RespireRx Pharmaceuticals Files September 30, 2016 Quarterly Report on Form 10-Q 237
6.20 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 239
6.21 Nov 15, 2016: ALung Technologies Forms Trial Steering Committee 240
6.22 Nov 14, 2016: Inspiration Healthcare Group: LifeStart Neonatal Resuscitation Unit Launched at MEDICA 2016 240
6.23 Nov 14, 2016: Capnia Reports Third Quarter 2016 Financial Results 241
6.24 Nov 10, 2016: Tenax Therapeutics Announces Third Quarter 2016 Financial Results and Provides Corporate Update 242
6.25 Nov 09, 2016: ZOLL Technology for Improving CPR Quality to be Showcased at American Heart Association Annual Conference 243
6.26 Nov 08, 2016: Ambu: Annual report 2015/16 244
6.27 Nov 03, 2016: Inogen Announces Third Quarter 2016 Financial Results 245
6.28 Nov 03, 2016: Mattias Perjos appointed President and CEO of Getinge Group 247
6.29 Nov 03, 2016: Enzymatica: ColdZyme sales continue to perform well 248
6.30 Nov 02, 2016: Masimo Reports Third Quarter 2016 Financial Results 248
6.31 Nov 01, 2016: Owens & Minor Releases 3rd Quarter 2016 Financial Results 249
6.32 Nov 01, 2016: GE Healthcare enhances single-use manufacturing capabilities with facility expansion and automation 251
6.33 Oct 31, 2016: Fresenius Medical Care to Acquire Xenios from ZFHN Zukunftsfonds 251
6.34 Oct 31, 2016: Cardinal Health Reports First-quarter Results for Fiscal Year 2017 251
6.35 Oct 31, 2016: Invacare Announces Financial Results for the Third Quarter and First Nine Months of 2016 252
6.36 Oct 27, 2016: United Therapeutics Reports Third Quarter 2016 Financial Results 257
6.37 Oct 27, 2016: Teleflex Reports Third Quarter 2016 Results 258
6.38 Oct 27, 2016: Adam Mikkelson of Camber Capital Management Joins Masimo’s Board of Directors 260
6.39 Oct 27, 2016: Teladoc Announces Third Quarter 2016 Results 261
6.40 Oct 26, 2016: Boston Scientific Announces Results For Third Quarter 2016 261
6.41 Oct 26, 2016: GlaxoSmithKline: Results Announcement for the third quarter 2016 263
6.42 Oct 25, 2016: Parion Sciences Announces Presentation of Clinical Data with Novel Pulmonary Delivery Device at the 2016 North American Cystic Fibrosis Conference 269
6.43 Oct 25, 2016: ResMed Announces Results for the First Quarter of Fiscal Year 2017 269
6.44 Oct 25, 2016: Invacare Announces New General Manager for Europe Segment 270
6.45 Oct 25, 2016: Dehaier Changes Name to Lianluo Smart Limited, Announces Strategic Personnel Adjustment and Announces Date of Annual Shareholder Meeting 271
6.46 Oct 25, 2016: Utah Medical Products Reports Financial Performance for Third Quarter 2016 272
6.47 Oct 18, 2016: Insmed Announces Publication of Phase 2 Study of ARIKAYCE in Treatment-Refractory Nontuberculous Mycobacterial Lung Disease 276
6.48 Oct 18, 2016: Further developed and focused strategy, and preparation for distribution of Patient & Post-Acute Care to shareholders of Getinge 278
6.49 Oct 18, 2016: Getinge Interim Report January-September 2016 278
6.50 Oct 17, 2016: Large US Emergency Department admissions reduced by 32% with use of Aerogen technology 281
6.51 Oct 11, 2016: Linde Healthcare Introduces Next Generation Therapeutic Oxygen Cylinder 282
6.52 Oct 10, 2016: Professor Ian Meredith To Join Boston Scientific As Executive Vice President And Global Chief Medical Officer 283
6.53 Oct 06, 2016: Pulmonx Completes Enrollment in U.S. Pivotal Trial of Zephyr Endobronchial Valve 283
6.54 Oct 05, 2016: Henry Ford Health System Announces New CEO of Health Alliance Plan 284
7 Appendix 474
7.1 Methodology 474
7.2 About GlobalData 476
7.3 Contact Us 476
7.4 Disclaimer 477

1.1 List of Tables
Table 1: Respiratory Devices - Pipeline Products by Stage of Development 30
Table 2: Respiratory Devices - Pipeline Products by Segment 31
Table 3: Respiratory Devices - Pipeline Products by Territory 32
Table 4: Respiratory Devices - Pipeline Products by Regulatory Path 33
Table 5: Respiratory Devices - Pipeline Products by Estimated Approval Date 34
Table 6: Respiratory Devices - Ongoing Clinical Trials 35
Table 7: Respiratory Devices Companies - Pipeline Products by Stage of Development 36
Table 8: Respiratory Devices - Pipeline Products by Stage of Development 40
Table 9: Ablynx NV Pipeline Products & Ongoing Clinical Trials Overview 45
Table 10: Customised Infant Inhalation Device - Product Status 45
Table 11: Customised Infant Inhalation Device - Product Description 46
Table 12: Advanced Circulatory Systems Inc Pipeline Products & Ongoing Clinical Trials Overview 47
Table 13: ResQVENT - Product Status 47
Table 14: ResQVENT - Product Description 47
Table 15: AerovectRx Corporation Pipeline Products & Ongoing Clinical Trials Overview 48
Table 16: Aerocurrent - Product Status 48
Table 17: Aerocurrent - Product Description 48
Table 18: Afalapi Pipeline Products & Ongoing Clinical Trials Overview 49
Table 19: Variable Positive Air Pressure (VPAP) Device - Product Status 49
Table 20: Variable Positive Air Pressure (VPAP) Device - Product Description 49
Table 21: AFT Pharmaceuticals Ltd Pipeline Products & Ongoing Clinical Trials Overview 50
Table 22: NasoSURF - Product Status 50
Table 23: NasoSURF - Product Description 50
Table 24: Airing LLC Pipeline Products & Ongoing Clinical Trials Overview 51
Table 25: Airing Device - Product Status 51
Table 26: Airing Device - Product Description 51
Table 27: Alaxo GmbH Pipeline Products & Ongoing Clinical Trials Overview 52
Table 28: AlaxoLito Nasal Stent - Product Status 52
Table 29: AlaxoLito Nasal Stent - Product Description 52
Table 30: AlaxoLito Plus Nasal Stent - Product Status 53
Table 31: AlaxoLito Plus Nasal Stent - Product Description 53
Table 32: AlaxoStent - Product Status 53
Table 33: AlaxoStent - Product Description 54
Table 34: Aloro Medical AB Pipeline Products & Ongoing Clinical Trials Overview 55
Table 35: Closed Breathing System - Product Status 55
Table 36: Closed Breathing System - Product Description 55
Table 37: ALung Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 56
Table 38: Hattler Catheter - Product Status 56
Table 39: Hattler Catheter - Product Description 57
Table 40: Hemolung Respiratory Assist System - Product Status 57
Table 41: Hemolung Respiratory Assist System - Product Description 58
Table 42: ALung Technologies Inc - Ongoing Clinical Trials Overview 59
Table 43: Hemolung Respiratory Assist System - Extra-corporeal CO2 Removal as an Adjunct to Non-Invasive Ventilation in Acute Severe Exacerbations of COPD 59
Table 44: Hemolung Respiratory Assist System - Physiological Study of Minimally Invasive Extracorporeal CO2 Removal in Exacerbations of COPD Requiring Invasive Mechanical Ventilation 60
Table 45: Hemolung Respiratory Assist System - Protective Ventilation with Veno-venous Lung Assist in Respiratory Failure 60
Table 46: Baby's Breath Ltd. Pipeline Products & Ongoing Clinical Trials Overview 61
Table 47: WiseAir - Product Status 61
Table 48: WiseAir - Product Description 61
Table 49: Beijing Dehaier Medical Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 62
Table 50: DHR-A8 Auto Continuous Positive Airway Pressure Device - Product Status 62
Table 51: DHR-A8 Auto Continuous Positive Airway Pressure Device - Product Description 63
Table 52: High-Efficiency Oxygen Inhaler - Product Status 63
Table 53: High-Efficiency Oxygen Inhaler - Product Description 63
Table 54: Second Generation CPAP Device - Product Status 64
Table 55: Second Generation CPAP Device - Product Description 64
Table 56: Second Generation Oxygen Concentrator - Product Status 64
Table 57: Second Generation Oxygen Concentrator - Product Description 65
Table 58: Blucore Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 66
Table 59: Breathing Device - Product Status 66
Table 60: Breathing Device - Product Description 66
Table 61: Breethe, Inc. Pipeline Products & Ongoing Clinical Trials Overview 67
Table 62: OXY-1 - Product Status 67
Table 63: OXY-1 - Product Description 67
Table 64: Broncus Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 68
Table 65: Exhale Drug Eluting Stent - Product Status 68
Table 66: Exhale Drug Eluting Stent - Product Description 68
Table 67: Capnia Inc Pipeline Products & Ongoing Clinical Trials Overview 69
Table 68: Serenz - Product Status 69
Table 69: Serenz - Product Description 70
Table 70: Case Western Reserve University Pipeline Products & Ongoing Clinical Trials Overview 71
Table 71: Portable Artificial Lung - Product Status 71
Table 72: Portable Artificial Lung - Product Description 71
Table 73: Circadiance LLC Pipeline Products & Ongoing Clinical Trials Overview 72
Table 74: Pediatric PAP Mask - NIV - Product Status 72
Table 75: Pediatric PAP Mask - NIV - Product Description 72
Table 76: Cleveland Medical Devices Inc Pipeline Products & Ongoing Clinical Trials Overview 73
Table 77: Auto-Titrating CPAP - Product Status 73
Table 78: Auto-Titrating CPAP - Product Description 73
Table 79: Coeo Labs Pvt Ltd Pipeline Products & Ongoing Clinical Trials Overview 74
Table 80: VAPCare - Product Status 74
Table 81: VAPCare - Product Description 74
Table 82: Coeo Labs Pvt Ltd - Ongoing Clinical Trials Overview 75
Table 83: VAPCare - A Preliminary Observational Study to Characterize Pattern of Pooling and Physical Properties of Secretions in Oral and Oropharyngeal Area in Patients on Ventilator Care 75
Table 84: Columbia Life Systems, Inc. Pipeline Products & Ongoing Clinical Trials Overview 76
Table 85: SmartBlender - Product Status 76
Table 86: SmartBlender - Product Description 76
Table 87: Creare Inc. Pipeline Products & Ongoing Clinical Trials Overview 77
Table 88: DDC-Based Nebulizer - Product Status 77
Table 89: DDC-Based Nebulizer - Product Description 77
Table 90: CSA Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 78
Table 91: RejuvenAir Metered Cryospray System - Product Status 78
Table 92: RejuvenAir Metered Cryospray System - Product Description 79
Table 93: CSA Medical Inc - Ongoing Clinical Trials Overview 79
Table 94: RejuvenAir Metered Cryospray System - A Prospective Safety and Feasibility Study of the RejuvenAir System Metered Cryospray Therapy for Chronic Bronchitis Patients 79
Table 95: Deca-Medics Inc Pipeline Products & Ongoing Clinical Trials Overview 80
Table 96: LifeBelt - CPR - Product Status 80
Table 97: LifeBelt - CPR - Product Description 80
Table 98: DesignWise Medical Inc. Pipeline Products & Ongoing Clinical Trials Overview 81
Table 99: OPOD System - Product Status 81
Table 100: OPOD System - Product Description 81
Table 101: Self-Contained Nebulizer System - Product Status 82
Table 102: Self-Contained Nebulizer System - Product Description 82
Table 103: Discover Medical Device Ltd. Pipeline Products & Ongoing Clinical Trials Overview 83
Table 104: SomnuSeal CPAP Mask - Product Status 83
Table 105: SomnuSeal CPAP Mask - Product Description 83
Table 106: SomnuSeal CPAP Mask Version 2.0 - Product Status 84
Table 107: SomnuSeal CPAP Mask Version 2.0 - Product Description 84
Table 108: Endoclear LLC Pipeline Products & Ongoing Clinical Trials Overview 85
Table 109: endOclear Wiper Device - Product Status 85
Table 110: endOclear Wiper Device - Product Description 85
Table 111: Filtara, Inc. Pipeline Products & Ongoing Clinical Trials Overview 86
Table 112: Lightweight Medical Oxygen Device - Product Status 86
Table 113: Lightweight Medical Oxygen Device - Product Description 86
Table 114: Fisher & Paykel Healthcare Corporation Limited Pipeline Products & Ongoing Clinical Trials Overview 87
Table 115: F&P 950 Heated Humidification System - Product Status 87
Table 116: F&P 950 Heated Humidification System - Product Description 88
Table 117: GE Healthcare Ltd Pipeline Products & Ongoing Clinical Trials Overview 89
Table 118: Ventilator - Neonates - Product Status 89
Table 119: Ventilator - Neonates - Product Description 89
Table 120: GeNO LLC Pipeline Products & Ongoing Clinical Trials Overview 90
Table 121: GeNOSYL Nitrosyl Delivery Platform - Ambulatory System - Product Status 90
Table 122: GeNOSYL Nitrosyl Delivery Platform - Ambulatory System - Product Description 90
Table 123: Hadassah Medical Center Pipeline Products & Ongoing Clinical Trials Overview 91

1.2 List of Figures
Figure 1: Respiratory Devices - Pipeline Products by Stage of Development 30
Figure 2: Respiratory Devices - Pipeline Products by Segment 31
Figure 3: Respiratory Devices - Pipeline Products by Territory 32
Figure 4: Respiratory Devices - Pipeline Products by Regulatory Path 33
Figure 5: Respiratory Devices - Pipeline Products by Estimated Approval Date 34
Figure 6: Respiratory Devices - Ongoing Clinical Trials 35