Summary
Global Markets Direct’s, ‘Astex Pharmaceuticals, Inc. - Product Pipeline Review - 2016’, provides an overview of the Astex Pharmaceuticals, Inc.’s pharmaceutical research and development focus.
The report provides comprehensive information on the therapeutics under development by Astex Pharmaceuticals, Inc., complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and the dormant and discontinued projects.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.
Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.
Scope
- The report provides a snapshot of the pipeline therapeutic landscape of Astex Pharmaceuticals, Inc.
- The report provides overview of Astex Pharmaceuticals, Inc. including its business description, key facts, and locations and subsidiaries
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report assesses Astex Pharmaceuticals, Inc.’s pipeline therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type
- The report features Astex Pharmaceuticals, Inc.’s out-licensed and partnered product portfolio and summarizes its dormant and discontinued projects
Reasons to buy
- Evaluate Astex Pharmaceuticals, Inc.’s strategic position with total access to detailed information on its product pipeline
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand important and diverse types of therapeutics under development for Astex Pharmaceuticals, Inc.
- Identify potential new clients or partners in the target demographic
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Astex Pharmaceuticals, Inc.’s pipeline depth and focus of pipeline therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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Table of Contents
Table of Contents 2
List of Tables 5
List of Figures 5
Astex Pharmaceuticals, Inc. Snapshot 6
Astex Pharmaceuticals, Inc. Overview 6
Key Information 6
Key Facts 6
Astex Pharmaceuticals, Inc. - Research and Development Overview 7
Key Therapeutic Areas 7
Astex Pharmaceuticals, Inc. - Pipeline Review 10
Pipeline Products by Stage of Development 10
Pipeline Products - Monotherapy 11
Pipeline Products - Combination Treatment Modalities 12
Pipeline Products - Out-Licensed Products 13
Out-Licensed Products/Combination Treatment Modalities 14
Astex Pharmaceuticals, Inc. - Pipeline Products Glance 15
Astex Pharmaceuticals, Inc. - Late Stage Pipeline Products 15
Phase III Products/Combination Treatment Modalities 15
Astex Pharmaceuticals, Inc. - Clinical Stage Pipeline Products 16
Phase II Products/Combination Treatment Modalities 16
Phase I Products/Combination Treatment Modalities 17
Astex Pharmaceuticals, Inc. - Early Stage Pipeline Products 18
Preclinical Products/Combination Treatment Modalities 18
Discovery Products/Combination Treatment Modalities 19
Astex Pharmaceuticals, Inc. - Drug Profiles 20
guadecitabine 20
Product Description 20
Mechanism of Action 20
R&D Progress 20
AT-7519 24
Product Description 24
Mechanism of Action 24
R&D Progress 24
AT-9283 27
Product Description 27
Mechanism of Action 27
R&D Progress 27
onalespib 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
(decitabine + E-7727) 32
Product Description 32
Mechanism of Action 32
R&D Progress 32
ASTX-660 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
AT-13148 35
Product Description 35
Mechanism of Action 35
R&D Progress 35
AT-26893 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
Small Molecules to Activate PKM2 for Lung Adenocarcinoma 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
Small Molecules to Inhibit MetAP2 for Colon Cancer 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
Small Molecule to Inhibit PAK1 for Oncology 40
Product Description 40
Mechanism of Action 40
R&D Progress 40
Small Molecules for Undisclosed Indication 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
Small Molecules to Antagonize DDR1 and DDR2 Receptors for Oncology 42
Product Description 42
Mechanism of Action 42
R&D Progress 42
Small Molecules to Inhibit TNIK for Oncology 43
Product Description 43
Mechanism of Action 43
R&D Progress 43
Astex Pharmaceuticals, Inc. - Pipeline Analysis 44
Astex Pharmaceuticals, Inc. - Pipeline Products by Target 44
Astex Pharmaceuticals, Inc. - Pipeline Products by Route of Administration 46
Astex Pharmaceuticals, Inc. - Pipeline Products by Molecule Type 47
Astex Pharmaceuticals, Inc. - Pipeline Products by Mechanism of Action 48
Astex Pharmaceuticals, Inc. - Recent Pipeline Updates 50
Astex Pharmaceuticals, Inc. - Dormant Projects 59
Astex Pharmaceuticals, Inc. - Discontinued Pipeline Products 60
Discontinued Pipeline Product Profiles 60
amuvatinib 60
onalespib 60
Astex Pharmaceuticals, Inc. - Locations And Subsidiaries 61
Head Office 61
Other Locations & Subsidiaries 61
Appendix 62
Methodology 62
Coverage 62
Secondary Research 62
Primary Research 62
Expert Panel Validation 62
Contact Us 62
Disclaimer 63
List of Tables
Astex Pharmaceuticals, Inc., Key Information 6
Astex Pharmaceuticals, Inc., Key Facts 6
Astex Pharmaceuticals, Inc. - Pipeline by Indication, 2016 8
Astex Pharmaceuticals, Inc. - Pipeline by Stage of Development, 2016 10
Astex Pharmaceuticals, Inc. - Monotherapy Products in Pipeline, 2016 11
Astex Pharmaceuticals, Inc. - Combination Treatment Modalities in Pipeline, 2016 12
Astex Pharmaceuticals, Inc. - Out-Licensed Products in Pipeline, 2016 13
Astex Pharmaceuticals, Inc. - Out-Licensed Products/ Combination Treatment Modalities, 2016 14
Astex Pharmaceuticals, Inc. - Phase III, 2016 15
Astex Pharmaceuticals, Inc. - Phase II, 2016 16
Astex Pharmaceuticals, Inc. - Phase I, 2016 17
Astex Pharmaceuticals, Inc. - Preclinical, 2016 18
Astex Pharmaceuticals, Inc. - Discovery, 2016 19
Astex Pharmaceuticals, Inc. - Pipeline by Target, 2016 44
Astex Pharmaceuticals, Inc. - Pipeline by Route of Administration, 2016 46
Astex Pharmaceuticals, Inc. - Pipeline by Molecule Type, 2016 47
Astex Pharmaceuticals, Inc. - Pipeline Products by Mechanism of Action, 2016 48
Astex Pharmaceuticals, Inc. - Recent Pipeline Updates, 2016 50
Astex Pharmaceuticals, Inc. - Dormant Developmental Projects,2016 59
Astex Pharmaceuticals, Inc. - Discontinued Pipeline Products, 2016 60
Astex Pharmaceuticals, Inc., Other Locations 61
Astex Pharmaceuticals, Inc., Subsidiaries 61
List of Figures
Astex Pharmaceuticals, Inc. - Pipeline by Top 10 Indication, 2016 8
Astex Pharmaceuticals, Inc. - Pipeline by Stage of Development, 2016 10
Astex Pharmaceuticals, Inc. - Monotherapy Products in Pipeline, 2016 11
Astex Pharmaceuticals, Inc. - Out-Licensed Products in Pipeline, 2016 13
Astex Pharmaceuticals, Inc. - Pipeline by Top 10 Target, 2016 44
Astex Pharmaceuticals, Inc. - Pipeline by Route of Administration, 2016 46
Astex Pharmaceuticals, Inc. - Pipeline by Molecule Type, 2016 47
Astex Pharmaceuticals, Inc. - Pipeline Products by Top 10 Mechanism of Action, 2016 48
