TABLE OF CONTENTS I
LIST OF FIGURES XXVII
LIST OF CHARTS XXXV
EXECUTIVE SUMMARY 1
EUROPEAN MARKET FOR VASCULAR ACCESS DEVICES AND ACCESSORIES OVERVIEW 1
COMPETITIVE ANALYSIS 3
MARKET TRENDS 5
MARKET DEVELOPMENTS 6
PROCEDURE NUMBERS 7
MARKETS INCLUDED 8
KEY REPORT UPDATES 11
VERSION HISTORY 12
RESEARCH METHODOLOGY 13
1.1 RESEARCH SCOPE 13
1.2 IDATA’S 9-STEP METHODOLOGY 13
Step 1: Project Initiation & Team Selection 13
Step 2: Prepare Data Systems and Perform Secondary Research 15
Step 3: Preparation for Interviews & Questionnaire Design 16
Step 4: Performing Primary Research 17
Step 5: Research Analysis: Establishing Baseline Estimates 19
Step 6: Market Forecast and Analysis 20
Step 7: Identify Strategic Opportunities 22
Step 8: Final Review and Market Release 23
Step 9: Customer Feedback and Market Monitoring 24
DISEASE OVERVIEW 25
2.1 BASIC ANATOMY 25
2.1.1 Human Vascular System 25
2.2 VASCULAR PATHOLOGY AND DISORDERS 26
2.2.1 Cancer 26
2.2.2 End-Stage Renal Disease 27
2.2.3 Diabetes 29
PRODUCT ASSESSMENT 32
3.1 PRODUCT PORTFOLIOS 32
3.1.1 Implantable Port Devices 32
3.1.1.1 Introduction 32
3.1.1.1.1 Implantable Port Patients 32
3.1.1.1.2 Port Implantation Procedures 33
3.1.1.1.3 Port Infusion 33
3.1.1.1.4 Port Maintenance 34
3.1.1.2 AngioDynamics 34
3.1.1.2.1 BioFlo® 34
3.1.1.2.2 LifePort® 34
3.1.1.2.3 Smart Port® CT 34
3.1.1.2.4 TitanPort® 34
3.1.1.2.5 Triumph-1® 35
3.1.1.2.6 Vortex® 35
3.1.1.2.7 Xcela™ Plus 35
3.1.1.3 B. Braun 35
3.1.1.3.1 Celsite® 35
3.1.1.4 Cook Medical 35
3.1.1.4.1 Vital-Port® 35
3.1.1.5 C.R. Bard 36
3.1.1.5.1 PowerPort® 36
3.1.1.5.2 SlimPort® 36
3.1.1.5.3 X-Port™ 36
3.1.1.5.4 Other Port Offerings 36
3.1.1.6 Medcomp 36
3.1.1.6.1 Dignity® 36
3.1.1.6.2 Pro-Fuse® CT 37
3.1.1.7 PFM Medical 37
3.1.1.7.1 T-Port™ 37
3.1.1.7.2 TitaJet™ 37
3.1.1.7.3 Jet Port® 37
3.1.1.7.4 DualPort 37
3.1.1.8 Smiths Medical 37
3.1.1.8.1 P.A.S. PORT® 37
3.1.1.8.2 PORT-A-CATH® 38
3.1.1.9 Teleflex Medical 38
3.1.1.9.1 Polysite® 38
3.1.2 Port Needles 39
3.1.2.1 Introduction 39
3.1.2.2 AngioDynamics 39
3.1.2.2.1 LifeGuard® 39
3.1.2.2.2 LifePort® 39
3.1.2.3 B. Braun 40
3.1.2.3.1 WHIN® 40
3.1.2.4 Cook Medical 40
3.1.2.4.1 Vital-Ject™ 40
3.1.2.5 C. R. Bard 40
3.1.2.5.1 PowerLoc® 40
3.1.2.5.2 Other Port Needle Offerings 40
3.1.2.6 Kawasumi 40
3.1.2.6.1 K-Shield® 40
3.1.2.6.2 Other Port Needle Offerings 41
3.1.2.7 MPS Medical, Inc. 41
3.1.2.7.1 SmartSafety® 41
3.1.2.8 Nipro Medical 41
3.1.2.8.1 SafeTouch™ 41
3.1.2.9 Smiths Medical 41
3.1.2.9.1 GRIPPER® 41
3.1.2.9.2 GRIPPER PLUS® 41
3.1.2.9.3 Other Port Needle Offerings 41
3.1.2.10 Vygon (Churchill Medical Systems) 42
3.1.2.10.1 LifeGuard™ 42
3.1.2.10.2 Wing Safe™ 42
3.1.3 Central Venous Catheters 43
3.1.3.1 Introduction 43
3.1.3.1.1 CVC Procedures 44
3.1.3.1.2 CVC Kits 44
3.1.3.1.3 CVC Market Segments 45
3.1.3.2 AngioDynamics 47
3.1.3.2.1 NeoStar™ 47
3.1.3.3 Centurion Medical Products 48
3.1.3.3.1 Vantex™ 48
3.1.3.3.2 Multi-Med™ 48
3.1.3.3.3 AVA™ 48
3.1.3.4 Cook Medical 48
3.1.3.4.1 Spectrum® 48
3.1.3.5 C.R. Bard 48
3.1.3.5.1 PowerHohn® 48
3.1.3.5.2 Hohn® 48
3.1.3.5.3 Other CVC Offerings 49
3.1.3.6 Medcomp Inc. 49
3.1.3.6.1 Pro-Line® 49
3.1.3.6.2 Vascu-Line® 49
3.1.3.6.3 Other CVC Offerings 49
3.1.3.7 Teleflex Medical 49
3.1.3.7.1 Standard 49
3.1.3.7.2 ARROWg+ard Blue® 49
3.1.3.7.3 ARROWg+ard Blue Plus® 50
3.1.3.7.4 Chlorag+ard® 50
3.1.4 Peripherally Inserted Central Catheters 51
3.1.4.1 Introduction 51
3.1.4.1.1 PICC Placement 51
3.1.4.2 AngioDynamics 52
3.1.4.2.1 BioFlo® 52
3.1.4.3 Argon Medical 53
3.1.4.3.1 First PICC™ 53
3.1.4.3.2 L-Cath™ 53
3.1.4.4 B. Braun 53
3.1.4.4.1 V-5™ 53
3.1.4.4.2 Other PICC Offerings 53
3.1.4.5 Cook Medical 53
3.1.4.5.1 Spectrum® 53
3.1.4.5.2 Other PICC Offerings 53
3.1.4.6 C.R. Bard 54
3.1.4.6.1 PowerPICC® 54
3.1.4.6.2 Groshong® 54
3.1.4.6.3 Per-Q-Cath® 54
3.1.4.6.4 Other PICC Offerings 54
3.1.4.7 GaltNeedleTech 54
3.1.4.7.1 SYNERGY™ 54
3.1.4.8 Medcomp 55
3.1.4.8.1 Pro-PICC™ 55
3.1.4.8.2 Vascu-PICC™ 55
3.1.4.9 Neo Medical 55
3.1.4.9.1 Neo-Magic™ 55
3.1.4.9.2 V-Cath™ 55
3.1.4.10 PFM Medical 55
3.1.4.10.1 pfm CT PICC II 55
3.1.4.11 Teleflex Medical 55
3.1.4.11.1 ARROW® 55
3.1.4.12 Trinity Sterile 56
3.1.4.12.1 Trinity™ PICC II 56
3.1.4.13 Vygon 56
3.1.4.13.1 Premicath™ 56
3.1.4.13.2 Epicutaneo-Cava™ 56
3.1.4.13.3 Nutriline™ 56
3.1.4.13.4 Lifecath™ 56
3.1.5 Peripheral Intravenous Catheters 57
3.1.5.1 Introduction 57
3.1.5.2 Access Scientific 58
3.1.5.2.1 POWERWAND® 58
3.1.5.3 AngioDynamics 58
3.1.5.3.1 BioFlo® 58
3.1.5.4 Argon Medical 58
3.1.5.4.1 First Midcath™ 58
3.1.5.4.2 L-Cath™ 58
3.1.5.5 B. Braun 58
3.1.5.5.1 Introcan Safety® 58
3.1.5.6 Becton Dickinson 59
3.1.5.6.1 Nexiva™ 59
3.1.5.6.2 Saf-T-Intima™ 59
3.1.5.6.3 Autoguard™ 59
3.1.5.7 C.R. Bard 59
3.1.5.7.1 AccuCath® 59
3.1.5.7.2 PowerGlide® 59
3.1.5.7.3 Bard® Poly 60
3.1.5.7.4 Other Midline Offerings 60
3.1.5.8 GaltNeedleTech 60
3.1.5.8.1 Nexus™ 60
3.1.5.9 Medcomp 60
3.1.5.9.1 Medcomp® Midline 60
3.1.5.10 MediKit 60
3.1.5.10.1 Supercath™ 60
3.1.5.11 Neo Medical 60
3.1.5.11.1 PowerStick™ 60
3.1.5.11.2 Neo-Magic® 61
3.1.5.12 Nipro Medical 61
3.1.5.12.1 Nipro™ IV Catheter 61
3.1.5.13 Retractable Technologies, Inc. 61
3.1.5.13.1 VanishPoint® 61
3.1.5.14 Smiths Medical 61
3.1.5.14.1 ViaValve™ 61
3.1.5.14.2 PROTECTIV® 61
3.1.5.14.3 ACUVANCE® 61
3.1.5.14.4 Other PIVC offerings 61
3.1.5.15 Tangent Medical 62
3.1.5.15.1 NovaCath™ 62
3.1.5.16 Teleflex Medical 62
3.1.5.16.1 ARROW® 62
3.1.5.16.2 TwinCath® 62
3.1.5.17 Terumo 62
3.1.5.17.1 SurFlash® 62
3.1.5.17.2 SURFLO® 62
3.1.5.18 Vygon 62
3.1.5.18.1 Leader-Flex™ 62
3.1.6 Dialysis Catheters 63
3.1.6.1 Introduction 63
3.1.6.1.1 AV Fistulae 63
3.1.6.1.2 AV Grafts 64
3.1.6.1.3 Dialysis Catheters 64
3.1.6.2 AngioDynamics 66
3.1.6.2.1 DuraMax® 66
3.1.6.2.2 DuraFlow™ 67
3.1.6.2.3 Schon™ 67
3.1.6.2.4 Other Dialysis Catheter Offerings 67
3.1.6.3 Argon Medical 67
3.1.6.3.1 UltraStream™ 67
3.1.6.4 Baxter 67
3.1.6.4.1 GamCath™ 67
3.1.6.5 Cook Medical 67
3.1.6.5.1 Turbo-Flo® 67
3.1.6.5.2 Tenckhoff™ 68
3.1.6.6 C.R. Bard 68
3.1.6.6.1 EQUISTREAM® 68
3.1.6.6.2 HemoSplit® 68
3.1.6.6.3 HemoStar® 68
3.1.6.6.4 Niagara™ 68
3.1.6.6.5 Other Dialysis Catheter Offerings 68
3.1.6.7 Marvao Medical 69
3.1.6.7.1 NexSite™ 69
3.1.6.8 Medcomp 69
3.1.6.8.1 Split Cath® 69
3.1.6.8.2 Hemo-Cath® 69
3.1.6.8.3 Hemo-Flow® 69
3.1.6.8.4 Other Dialysis Catheter Offerings 69
3.1.6.9 Medtronic 70
3.1.6.9.1 MAHURKAR™ 70
3.1.6.9.2 Palindrome™ 70
3.1.6.9.3 Other Dialysis Catheter Offerings 70
3.1.6.10 Merit Medical 70
3.1.6.10.1 Flex-Neck® 70
3.1.6.10.2 Centros™ 70
3.1.6.10.3 ProGuide™ 71
3.1.6.11 PFM Medical 71
3.1.6.11.1 Veta™ 71
3.1.6.12 Phase One Medical 71
3.1.6.12.1 Symetrex™ 71
3.1.6.13 Teleflex Medical 71
3.1.6.13.1 NextStep® 71
3.1.6.13.2 VectorFlow™ 71
3.1.6.13.3 Other Dialysis Catheter Offerings 71
3.1.7 Ultrasound Vascular Access Devices 72
3.1.7.1 Introduction 72
3.1.7.1.1 Alternates to Ultrasound Guidance 72
3.1.7.1.2 Ultrasound Guidance 73
3.1.7.1.3 Ultrasound Vessel Mapping 74
3.1.7.1.4 Tip Location 74
3.1.7.1.5 General Ultrasound Imaging Systems with Vascular Access Guidance Capabilities Market 76
3.1.7.2 Analogic 76
3.1.7.2.1 Sonic Window™ 76
3.1.7.3 AngioDynamics 76
3.1.7.3.1 Celerity™ 76
3.1.7.4 Chison 76
3.1.7.4.1 EC0™ 76
3.1.7.4.2 Other Ultrasound Offerings 77
3.1.7.5 C.R. Bard 77
3.1.7.5.1 Site~Rite® 77
3.1.7.5.2 Sherlock® 77
3.1.7.6 Esaote North America 77
3.1.7.6.1 MyLab™ 77
3.1.7.7 eZono 77
3.1.7.7.1 eZono® 77
3.1.7.8 FUJIFILM SonoSite, Inc. 78
3.1.7.8.1 S Series™ 78
3.1.7.8.2 NanoMaxx® 78
3.1.7.8.3 Edge® II 78
3.1.7.8.4 M-Turbo® 78
3.1.7.8.5 iViz® 78
3.1.7.9 GE Healthcare 78
3.1.7.9.1 Vscan™ 78
3.1.7.9.2 LOGIQ™ 79
3.1.7.9.3 Venue™ 79
3.1.7.10 Konica Minolta 79
3.1.7.10.1 Sonimage™ P3 79
3.1.7.11 Medcomp 79
3.1.7.11.1 Navigator® BioNavigation™ 79
3.1.7.12 Mobisante 79
3.1.7.12.1 MobiUS™ 79
3.1.7.13 Philips 80
3.1.7.13.1 Lumify™ 80
3.1.7.14 Romedex 80
3.1.7.14.1 Nautilus™ 80
3.1.7.15 Siemens 80
3.1.7.15.1 ACUSON™ 80
3.1.7.16 SIUI 80
3.1.7.16.1 Apogee™ 80
3.1.7.16.2 CTS™ 81
3.1.7.17 SonoScape 81
3.1.7.17.1 S™ 81
3.1.7.17.2 A™ 81
3.1.7.18 Teleflex Medical 81
3.1.7.18.1 ARROW® VPS® 81
3.1.7.19 Terason 81
3.1.7.19.1 uSmart® 81
3.1.7.20 Toshiba 82
3.1.7.20.1 Viamo™ 82
3.1.7.21 Zonare 82
3.1.7.21.1 M™ 82
3.1.7.21.2 Other Ultrasound Offerings 82
3.1.8 Catheter Securement Devices 83
3.1.8.1 Introduction 83
3.1.8.1.1 Catheter Stabilization Methods 83
3.1.8.2 3M 85
3.1.8.2.1 3M™ PICC/CVC Securement Systems 85
3.1.8.2.2 Tegaderm™ 85
3.1.8.2.3 3M™ Medical Tapes 86
3.1.8.3 Baxter 86
3.1.8.3.1 VITAL-HOLD™ 86
3.1.8.4 Cardinal Health 86
3.1.8.4.1 Original Boarder 86
3.1.8.4.2 Advanced IV 86
3.1.8.5 Centurion Medical 86
3.1.8.5.1 SorbaView® 86
3.1.8.5.2 Other Product Offerings 87
3.1.8.6 C.R. Bard 87
3.1.8.6.1 StatLock® IV 87
3.1.8.6.2 StatLock® PICC 87
3.1.8.6.3 StatLock® CV 88
3.1.8.6.4 StatLock® Dialysis 88
3.1.8.6.5 Other StatLock® Offerings 88
3.1.8.7 Insightra Medical 88
3.1.8.7.1 Modulare® 88
3.1.8.8 Interrad Medical 88
3.1.8.8.1 SecurAcath® 88
3.1.8.9 Johnson & Johnson 89
3.1.8.9.1 BioPatch® 89
3.1.8.9.2 Other Product Offerings 89
3.1.8.10 M.C. Johnson 90
3.1.8.10.1 CATH-SECURE™ 90
3.1.8.11 Medtronic 90
3.1.8.11.1 Kendall™ 90
3.1.8.11.2 Other Product Offerings 90
3.1.8.12 Neo Medical 90
3.1.8.12.1 V-Lock™ 90
3.1.8.13 Smith & Nephew 90
3.1.8.13.1 IV3000® 90
3.1.8.13.2 HYPAFIX® 90
3.1.8.13.3 PRIMAPORE® 91
3.1.8.14 Starboard Medical 91
3.1.8.14.1 CLIK-IT™ 91
3.1.8.15 TIDI Products 91
3.1.8.15.1 Grip-Lok® PICC Securement 91
3.1.8.15.2 Grip-Lok® CVC Securement 91
3.1.8.15.3 Grip-Lok® PIVC Securement 91
3.1.9 Syringe and Needles 92
3.1.9.1 Introduction 92
3.1.9.2 Allison Medical 93
3.1.9.2.1 SureComfort™ 93
3.1.9.3 B. Braun 94
3.1.9.3.1 Injekt® 94
3.1.9.3.2 Other Syringe & Needle Offerings 94
3.1.9.4 Becton Dickinson 94
3.1.9.4.1 BD™ Insulin Syringes 94
3.1.9.4.2 BD™ Allergy Syringes 94
3.1.9.4.3 BD™ Tuberculin Syringes 94
3.1.9.4.4 BD™ Syringes & Needles 95
3.1.9.4.5 BD PrecisionGlide™ Needles 95
3.1.9.4.6 BD Safety-Lok™ Syringes 95
3.1.9.4.7 BD SafetyGlide™ Syringes & Needles 95
3.1.9.4.8 BD Eclipse™ Needles and Syringes 95
3.1.9.4.9 BD Integra™ Needles and Syringes 96
3.1.9.4.10 BD AutoShield™ 96
3.1.9.4.11 Ultra-Fine™ 96
3.1.9.5 Cardinal Health 96
3.1.9.5.1 Cardinal Health™ 96
3.1.9.6 Delta Hi-Tech, Inc. 96
3.1.9.6.1 AIMSCO® 96
3.1.9.7 Medical Plastic Devices, Inc. 97
3.1.9.7.1 Insupen® 97
3.1.9.8 Medtronic 97
3.1.9.8.1 Magellan™ 97
3.1.9.8.2 Monoject™ 97
3.1.9.9 MYCO Medical 97
3.1.9.9.1 Dispovan® 97
3.1.9.10 Nipro Medical 97
3.1.9.10.1 Nipro™ 97
3.1.9.11 Novo Nordisk 98
3.1.9.11.1 NovoFine® 98
3.1.9.11.2 NovoTwist® 98
3.1.9.12 Owen Mumford, Inc. 98
3.1.9.12.1 Unifine® 98
3.1.9.13 Perrigo 98
3.1.9.13.1 Clickfine® 98
3.1.9.14 Protectus Medical Devices 98
3.1.9.14.1 Protectus® 98
3.1.9.15 ReliOn 99
3.1.9.15.1 ReliOn® 99
3.1.9.16 Retractable Technologies, Inc. 99
3.1.9.16.1 VanishPoint® 99
3.1.9.16.2 Patient Safe® 99
3.1.9.17 Revolutions Medical 99
3.1.9.17.1 ReVac™ 99
3.1.9.18 Safety 1st Medical 99
3.1.9.18.1 Safe-1® 99
3.1.9.19 Smiths Medical 99
3.1.9.19.1 Needle-Pro® 99
3.1.9.20 SOL-MILLENNIUM 100
3.1.9.20.1 SOL-CARE® 100
3.1.9.20.2 SOL-M™ 100
3.1.9.20.3 SOL-GUARD™ 100
3.1.9.21 STAT Medical Devices 100
3.1.9.21.1 Super-Fine™ 100
3.1.9.22 Terumo 101
3.1.9.22.1 SurGuard® 101
3.1.9.22.2 TERUMO® 101
3.1.9.23 UltiCare 101
3.1.9.23.1 UltiCare® 101
3.2 REGULATORY ISSUES AND RECALLS 102
3.2.1 November 2015 102
3.2.2 October 2015 102
3.2.3 September 2015 103
3.2.4 August 2015 105
3.2.5 July 2015 106
3.2.6 April 2015 108
3.2.7 March 2015 109
3.2.8 February 2015 110
3.2.9 January 2015 110
3.2.10 December 2014 111
3.2.11 October 2014 112
3.2.12 September 2014 113
3.2.13 May 2014 114
3.2.14 April 2014 114
3.2.15 March 2014 115
3.2.16 January 2014 115
3.2.17 December 2013 116
3.2.18 September 2013 117
3.2.19 August 2013 118
3.2.20 June 2013 118
3.2.21 March 2013 119
3.2.22 February 2013 120
3.2.23 December 2012 120
3.2.24 August 2012 120
3.2.25 June 2012 121
3.2.26 May 2012 122
3.2.27 March 2012 123
3.2.28 February 2012 124
3.2.29 January 2012 124
3.3 CLINICAL TRIALS 128
3.3.1 Implantable Port Devices 129
3.3.2 Central Venous Catheters 131
3.3.3 Peripherally Inserted Central Catheters 145
3.3.4 Peripheral Intravenous Catheters 155
3.3.5 Dialysis Catheters 164
3.3.6 Ultrasound Vascular Access Devices 170
3.3.7 Catheter Securement Devices 185
3.3.8 Syringe and Needles 187
3.4 PRODUCT PIPELINES 197
3.4.1 Alliance Vascular Devices, LLC 197
3.4.1.1 FreeHand Safety Huber Needle® 197
3.4.2 AngioDynamics 197
3.4.2.1 Celerity™ PICC Tip Confirmation System with Navigation 197
3.4.2.2 Firefly 197
3.4.2.3 BioFlo® PICC Line Extension 198
3.4.2.4 BioFlo® Port Line Extension 198
3.4.2.5 Next Generation BioFlo® PICC 198
3.4.2.6 Next Generation BioFlo® Port 198
3.4.3 Bluegrass Vascular Technologies, Inc. 198
3.4.3.1 Surfacer® Inside-Out™ Access System 198
3.4.4 C.R. Bard 198
3.4.4.1 Chemical-Resistant PICCs 198
3.4.4.2 Novel Advanced Material PICCs 199
3.4.4.3 PowerGlide® Pro Midline 199
3.4.4.4 AccuCath® 199
3.4.4.5 Xenesis™ Acute Hemodialysis Catheter 199
3.4.4.6 Site~Rite® 8 Ultrasound System 199
3.4.5 M. C. Johnson 199
3.4.5.1 PICC Securement Device 199
3.4.6 Nipro Medical 200
3.4.6.1 Shielding Safety Needle 200
3.4.6.2 Safety Syringe 200
3.4.6.3 Safety PIVC 200
3.4.7 Parasol Medical 200
3.4.7.1 Catheter Securement Device 200
3.4.8 PAVmed Inc. 200
3.4.8.1 NextCath™ 200
3.4.9 Phase One Medical 200
3.4.9.1 Goldilocks™ Long Term Hemodialysis Catheter 200
3.4.9.2 Triple-Lumen Symetrex™ Hemodialysis Catheter 201
3.4.10 Prodigy Diabetes Care, LLC. 201
3.4.10.1 Insulin Pen Needles 201
3.4.11 Sharklet Technologies, Inc. 201
3.4.11.1 Sharklet™ Central Venous Catheter 201
3.4.12 Starboard Medical 201
3.4.12.1 Catheter Securement Devices 201
3.4.13 Teleflex Medical 202
3.4.13.1 Arrow® Endurance™ Extended Dwell Peripheral Catheter System 202
3.4.13.2 Tip Confirmation for CVCs, Chronic Hemodialysis Catheters & Ports 202
3.4.14 Vascular Access Technologies, Inc. 202
3.4.14.1 SAFECVAD™ 202
COUNTRY PROFILES 203
4.1 INTRODUCTION 203
4.1.1 Population 203
4.1.2 GDP Per Capita 203
4.1.3 Price Index 203
4.2 GERMANY 204
4.3 FRANCE 205
4.4 UNITED KINGDOM 206
4.5 ITALY 207
4.6 SPAIN 208
4.7 BENELUX 209
4.8 SCANDINAVIA 210
4.9 AUSTRIA 211
4.10 SWITZERLAND 212
4.11 PORTUGAL 213
ABBREVIATIONS 214
APPENDIX II: COMPANY PRESS RELEASES 216

Chart 1 1: Vascular Access Device and Accessories Market by Segment, Europe, 2013 – 2023 2
Chart 1 2: Vascular Access Device and Accessories Market Overview, Europe, 2016 & 2023 2
Chart 3 1: Central Venous Catheter Market Segments, 2015 45
Chart 4 1: Country Profile, Germany, 2016 204
Chart 4 2: Country Profile, France, 2016 205
Chart 4 3: Country Profile, United Kingdom, 2016 206
Chart 4 4: Country Profile, Italy, 2016 207
Chart 4 5: Country Profile, Spain, 2016 208
Chart 4 6: Country Profile, Benelux, 2016 209
Chart 4 7: Country Profile, Scandinavia, 2016 210
Chart 4 8: Country Profile, Austria, 2016 211
Chart 4 9: Country Profile, Switzerland, 2016 212
Chart 4 10: Country Profile, Portugal, 2016 213

Figure 1 1: Vascular Access Device and Accessories Competitor Market Share Ranking by Segment, Europe, 2016 (1 of 2) 3
Figure 1 2: Vascular Access Device and Accessories Competitor Market Share Ranking by Segment, Europe, 2016 (2 of 2) 3
Figure 1 3: Companies Researched in this Report, Europe, 2016 4
Figure 1 4: Factors Impacting the Vascular Access Device and Accessories Market by Segment, Europe, 2016 5
Figure 1 5: Recent Events in the Vascular Access Device and Accessories Market, Europe, 2013 – 2016 6
Figure 1 6: Vascular Access Procedures Covered, Europe, 2016 7
Figure 1 7: Vascular Access Device and Accessories Markets Covered, Europe, 2016 (1 of 3) 8
Figure 1 8: Vascular Access Device and Accessories Markets Covered, Europe, 2016 (2 of 3) 9
Figure 1 9: Vascular Access Device and Accessories Markets Covered, Europe, 2016 (3 of 3) 10
Figure 1 10: Key Report Updates 11
Figure 1 11: Version History 12
Figure 3 1: Class 2 Device Recall Medtronic 102
Figure 3 2: Class 2 Device Recall Smiths Medical 102
Figure 3 3: Class 2 Device Recall Arrow 103
Figure 3 4: Class 2 Device Recall Arrow 103
Figure 3 5: Class 2 Device Recall Covidien (Medtronic) 104
Figure 3 6: Class 2 Device Recall Arrow 105
Figure 3 7: Class 2 Device Recall Medline 105
Figure 3 8: Class 2 Device Recall Arrow 105
Figure 3 9: Class 2 Device Recall B. Braun 105
Figure 3 10: Class 3 Device Recall Bard Access 106
Figure 3 11: Class 2 Device Recall Covidien (Medtronic) 106
Figure 3 12: Class 2 Device Recall Bard Access 108
Figure 3 13: Class 2 Device Recall Bard Access 108
Figure 3 14: Class 2 Device Recall Medcomp & AngioDynamics 109
Figure 3 15: Class 2 Device Recall Bard Access 109
Figure 3 16: Class 2 Device Recall Arrow 110
Figure 3 17: Class 2 Device Recall Medcomp 110
Figure 3 18: Class 2 Device Recall Arrow 110
Figure 3 19: Class 2 Device Recall Arrow 111
Figure 3 20: Class 2 Device Recall Smiths Medical 111
Figure 3 21: Class 2 Device Recall PFM Medical 111
Figure 3 22: Class 2 Device Recall PFM Medical 111
Figure 3 23: Class 2 Device Recall Becton Dickinson 112
Figure 3 24: Class 2 Device Recall Arrow 112
Figure 3 25: Class 2 Device Recall Arrow 112
Figure 3 26: Class 2 Device Recall Navilyst Medical 112
Figure 3 27: Class 2 Device Recall Argon Medical 113
Figure 3 28: Class 2 Device Recall Arrow 114
Figure 3 29: Class 2 Device Recall Arrow 114
Figure 3 30: Class 2 Device Recall Arrow 115
Figure 3 31: Class 2 Device Recall Bard Access 115
Figure 3 32: Class 2 Device Recall Navilyst Medical 115
Figure 3 33: Class 2 Device Recall Bard Access 116
Figure 3 34: Class 2 Device Recall Smiths Medical 116
Figure 3 35: Class 2 Device Recall B. Braun 116
Figure 3 36: Class 2 Device Recall Smiths Medical 117
Figure 3 37: Class 2 Device Recall Access Scientific 117
Figure 3 38: Class 2 Device Recall Covidien (Medtronic) 117
Figure 3 39: Class 2 Device Recall Arrow 118
Figure 3 40: Class 2 Device Recall Bard Access 118
Figure 3 41: Class 2 Device Recall Becton Dickinson 118
Figure 3 42: Class 2 Device Recall Churchill Medical Systems, Inc. A Vygon Company 119
Figure 3 43: Class 2 Device Recall Bard Access 119
Figure 3 44: Class 2 Device Recall Churchill Medical Systems, Inc. A Vygon Company 119
Figure 3 45: Class 2 Device Recall Medcomp 120
Figure 3 46: Class 2 Device Recall Becton Dickinson 120
Figure 3 47: Class 3 Device Recall Bard Access 120
Figure 3 48: Class 2 Device Recall Medcomp 121
Figure 3 49: Class 1 Device Recall Arrow 121
Figure 3 50: Class 2 Device Recall Arrow 121
Figure 3 51: Class 2 Device Recall Vygon 121
Figure 3 52: Class 2 Device Recall Covidien (Medtronic) 122
Figure 3 53: Class 2 Device Recall Medcomp 123
Figure 3 54: Class 2 Device Recall Churchill Medical Systems, Inc. A Vygon Company 123
Figure 3 55: Class 2 Device Recall Christie Medical Holdings 123
Figure 3 56: Class 3 Recall Bard Access 123
Figure 3 57: Class 2 Device Recall AngioDynamics 124
Figure 3 58: Class 2 Device Recall Becton Dickinson 124
Figure 3 59: Class 2 Device Recall AngioDynamics 124
Figure 3 60: Class 2 Device Recall AngioDynamics 126
Figure 3 61: Class 3 Device Recall AngioDynamics 127
Figure 3 62: Class 2 Device Recall AngioDynamics 127
Figure 3 63: Bone Anchored Port - a Novel Vascular Access for Hemodialysis Treatment 129
Figure 3 64: A Pragmatic Randomized Trial 129
Figure 3 65: Assessment of a Power Injectable vs. a Non-Power Injectable 130
Figure 3 66: Vascular Access in Cancer Patients 130
Figure 3 67: Ultrasound-guided Subclavian Vein Puncture Versus Cephalic Vein Dissection 130
Figure 3 68: Central Line Placement Study 131
Figure 3 69: The Effects of Anti-infective Central Venous Catheter (CVC) 131
Figure 3 70: The Use of Point of Care Ultra Sound 132
Figure 3 71: Complications Associated With Central Venous Access 132
Figure 3 72: Impact of Ultrasound Guided Central Venous Catheterization 133
Figure 3 73: Randomized, Prospective, Single-center Study 133
Figure 3 74: Remifentanil and Local Anesthesia 134
Figure 3 75: Dissemination of a Simulation-based Mastery Learning Curriculum 134
Figure 3 76: Incidence of Complication 135
Figure 3 77: Comparison of Two Needle Insertion Techniques 135
Figure 3 78: A Monocenter Prospective Study 136
Figure 3 79: A Prospective Study to Compare Point of Care Echocardiography Versus Chest Radiography 136
Figure 3 80: Long-versus Short-Axis Ultrasound Guidance for Subclavian Vein Cannulation 137
Figure 3 81: Use of Chlorhexidine-gel-Impregnated Dressing Compared to Transparent Polyurethane Film Dressing 137
Figure 3 82: Vascular Access in Hematological Patients 138
Figure 3 83: Developing and Maintaining a Central Venous Catheter Registry 138
Figure 3 84: Reliability of Central Venous Pressure Measurements 138
Figure 3 85: SUBclavian Central Venous Catheters Guidance and Examination by UltraSound 139
Figure 3 86: Chlorhexidine Containing IV-securement Dressings 139
Figure 3 87: Comparison of Effectiveness and Safety of Two Methods for Installing Femoral Central Venous Catheters 140
Figure 3 88: A Phase III Study of Peripherally Inserted Versus Centrally Inserted Central Venous Catheters 140
Figure 3 89: Ultrasound Guided Diagnosis of Central Venous Catheters in Children 141
Figure 3 90: Real-time Ultrasound-guided Catheterization of the Axillary Vein in the Intensive Care Unit 141
Figure 3 91: Determination of Anatomic Variations of the Internal Jugular and Femoral Veins 142
Figure 3 92: Comparison of Subclavian, Femoral and Internal Jugular Venous Catheterization 142
Figure 3 93: Landmark vs. Ultrasound Guided Subclavian Central Venous Catheter Placement 143
Figure 3 94: Interest of Ultrasound Coupled to a Guidance System (GPS) 143
Figure 3 95: Risk of Central Venous Stenosis in Patients With Chronic Renal Failure After IJ Line Placement 144
Figure 3 96: Comparison of the Central Venous Catheter Insertion Techniques 144
Figure 3 97: A Multicenter, Open-label, Randomised, Clinical Trial 145
Figure 3 98: A Pragmatic Randomized Trial Standard of Care Vascular Access Strategies 145
Figure 3 99: PICC and Midline Related Complications: A Multicenter Observational Study 146
Figure 3 100: Complications Associated With Central Venous Access 146
Figure 3 101: Evaluation of Electrocardiographic Guidance 146
Figure 3 102: Phase II Randomised Study Comparing the Tolerance of PICC Line 147
Figure 3 103: Randomized, Prospective, Single-center Study 147
Figure 3 104: A Randomized Controlled Trial Comparing Ultrasound Guided PICC Line Insertion 148
Figure 3 105: Ultrasound-guided Peripheral Vascular Access 148
Figure 3 106: Vascular Access in Cancer Patients 149
Figure 3 107: A Monocenter Prospective Study 150
Figure 3 108: Vascular Access in Hematological Patients 150
Figure 3 109: ECG Versus Ultrasound-guided Positioning of the Peripherally Inserted Central Catheter (PICC) Tip 150
Figure 3 110: Sequential Pneumatic Compression 151
Figure 3 111: Reliability of Central Venous Pressure Measurements 151
Figure 3 112: Time and Motion Related to PICC Insertion Process and Catheter Tip Confirmation 152
Figure 3 113: A Randomized Open-labeled Multicenter Study 152
Figure 3 114: A Phase III Study of Peripherally Inserted Versus Centrally Inserted Central Venous Catheters 153
Figure 3 115: A Randomized Prospective Multicenter Evaluation 153
Figure 3 116: Randomized Double Blind Comparison 154
Figure 3 117: An Observational, Prospective, Single-center Study of Placement and Confirmation 154
Figure 3 118: PICC and Midline Related Complications 155
Figure 3 119: Contribution of Ultrasound for Peripheral Intravenous Catheter Placement by Intensive Care Nurses 155
Figure 3 120: A Comparison of Accuvein to Standard Intravenous Access 156
Figure 3 121: Randomized, Controlled Study of Ultrasound-Guided Peripheral Venous Access 156
Figure 3 122: Pen Torch Transillumination: Shedding Light on Difficult Venepuncture 157
Figure 3 123: Ultrasound-guided Peripheral Vascular Access in Children 157
Figure 3 124: Preventing Delay of Care in Patient With Difficult IV Access 158
Figure 3 125: A Randomized Control Trial of Ultrasound Guided IV Access 158
Figure 3 126: Removal Peripheral Intravenous Catheters According to Clinical Signs 159
Figure 3 127: Clinical Investigation Acc. to MPG §23b 159
Figure 3 128: Evaluation of Accuvein® in Obese Patients 159
Figure 3 129: A Randomized, Open Label Study to Evaluate the Effectiveness of the MMT Initial Specimen Diversion Device 160
Figure 3 130: Technique for Successful Ultrasound-guided Peripheral Vascular Access 160
Figure 3 131: A Randomized Controlled Open Label Trial 160
Figure 3 132: A Prospective Feasibility Trial of AccuCath® 2.25" BC Intravascular Catheter System 161
Figure 3 133: The Use of a Topical Anesthetic Skin Refrigerant 161
Figure 3 134: A Randomized Controlled Trial to Demonstrate the Safety and Efficacy of the OptiVein® IV Catheter 162
Figure 3 135: Observational Study of the Sonic Window™ Handheld Ultrasound System 162
Figure 3 136: Near-Infrared Software Performance Study 162
Figure 3 137: A Randomized Controlled Trial To Compare The Initial Success Rate 163
Figure 3 138: A Clinical Assessment of an Ultrasound-guided Inserted Peripheral Intravenous Catheter 163
Figure 3 139: Ultrasound Guided Peripheral Intravenous Catheter Insertion 163
Figure 3 140: Nurse Peripheral Intravenous Catheter Insertion Success 164
Figure 3 141: ACCESS HD Pilot 164
Figure 3 142: Randomized Controlled Trial of Straight Versus Coiled Peritoneal Dialysis 165
Figure 3 143: Randomized Trial Comparing VectorFlow™ Tunneled Dialysis Catheter 165
Figure 3 144: Duration and Adverse Events of Non-cuffed Catheter 165
Figure 3 145: Vascular Access Choice and Outcomes in the Elderly and Very Elderly 166
Figure 3 146: Prevention of Tunneled Cuffed Catheter Malfunction 166
Figure 3 147: Analysis of CRBSI 167
Figure 3 148: A Prospective Multicenter Investigation 167
Figure 3 149: Comparison of an Intensive Versus a Standard Hemodialysis Central Venous Catheter 167
Figure 3 150: Post Marketing Surveillance of the CentrosFLO™ Tunneled IJ Catheter for Dialysis 168
Figure 3 151: Comparison of Self-locating Catheter Versus a Straight Catheter for Outflow Problems 168
Figure 3 152: Multi-Center, Prospective, Randomized, Open-Label, Sponsor-Blinded, Active-Control (Heparin) Clinical Investigation 169
Figure 3 153: Comparative Effectiveness of 30% Trisodium Citrate and Heparin Lock Solutions 169
Figure 3 154: The Use of Point of Care Ultra Sound for Correct Placement 170
Figure 3 155: Contribution of Ultrasound for Peripheral Intravenous Catheter 170
Figure 3 156: Evaluation of Electrocardiographic Guidance 171
Figure 3 157: Impact of Ultrasound Guided Central Venous Catheterization 171
Figure 3 158: A Comparison of Accuvein to Standard Intravenous Access 171
Figure 3 159: Randomized, Controlled Study of Ultrasound-Guided Peripheral Venous Access 172
Figure 3 160: Pen Torch Transillumination: Shedding Light on Difficult Venepuncture 172
Figure 3 161: Incidence of Complication Depending on the Cannulation Site 173
Figure 3 162: A Randomized Controlled Trial Comparing Ultrasound Guided PICC Line Insertion 173
Figure 3 163: Ultrasound-guided Peripheral Vascular Access in Children 174
Figure 3 164: Preventing Delay of Care in Patient With Difficult IV Access 174
Figure 3 165: Ultrasound-guided Peripheral Vascular Access 175
Figure 3 166: A Randomized Control Trial of Ultrasound Guided IV Access 175
Figure 3 167: Long-versus Short-Axis Ultrasound Guidance for Subclavian Vein Cannulation 176
Figure 3 168: A Prospective Study to Compare Point of Care Echocardiography Versus Chest Radiography 176
Figure 3 169: ECG Versus Ultrasound-guided Positioning 176
Figure 3 170: SUBclavian Central Venous Catheters Guidance and Examination 177
Figure 3 171: Evaluation of Accuvein® in Obese Patients 177
Figure 3 172: Time and Motion Related to PICC Insertion Process 178
Figure 3 173: Technique for Successful Ultrasound-guided Peripheral Vascular Access 178
Figure 3 174: A Randomized Open-labeled Multicenter Study 179
Figure 3 175: Comparison of Effectiveness and Safety of Two Methods for Installing Femoral Central Venous Catheters 179
Figure 3 176: Ultrasound Guided Diagnosis of Central Venous Catheters in Children 180
Figure 3 177: Real-time Ultrasound-guided Catheterization of the Axillary Vein 180
Figure 3 178: Observational Study of the Sonic Window™ Handheld Ultrasound System 181
Figure 3 179: Ultrasound-guided Subclavian Vein Puncture 181
Figure 3 180: Near-Infrared Software Performance Study 181
Figure 3 181: Landmark vs. Ultrasound Guided Subclavian Central Venous Catheter Placement 182
Figure 3 182: Interest of Ultrasound Coupled to a Guidance System (GPS) 182
Figure 3 183: A Randomized Controlled Trial 183
Figure 3 184: A Clinical Assessment of an Ultrasound-guided Inserted Peripheral Intravenous Catheter 183
Figure 3 185: Ultrasound Guided Peripheral Intravenous Catheter Insertion 183
Figure 3 186: An Observational, Prospective, Single-center Study 184
Figure 3 187: Nurse Peripheral Intravenous Catheter Insertion Success 184
Figure 3 188: Unit Based Comparison of Non-Versus Chlorhexidine-Impregnated Central Line Dressings 185
Figure 3 189: Use of Chlorhexidine-gel-Impregnated Dressing 185
Figure 3 190: Comparing SecurAcath® Versus StatLock® 186
Figure 3 191: Chlorhexidine Containing Iv-securement Dressings 186
Figure 3 192: A Randomized, Parallel Design Study 187
Figure 3 193: Pen Torch Transillumination: Shedding Light on Difficult Venepuncture 187
Figure 3 194: Transition From Parenteral Prostanoids to Inhaled Treprostinil 188
Figure 3 195: Efficacy, Safety and Acceptability of the New Pen Needle 188
Figure 3 196: A Phase I Study of the Safety, Reactogenicity, Acceptability and Immunogenicity 189
Figure 3 197: A Single Centre, Randomised, 3-period Cross-over Trial 189
Figure 3 198: A Phase IV, Non-Inferiority, Observer Blind, Randomized Clinical Study 190
Figure 3 199: Treating Diabetic Lipohypertrophy With Intensive Education 190
Figure 3 200: Pharmacokinetic Comparison of Intradermal Versus Sub-cutaneous Insulin 191
Figure 3 201: A Randomized, Multi-centre Cross-over Study 191
Figure 3 202: A Clinical Investigation to Evaluate the Safety and Performance 192
Figure 3 203: A Phase I, Randomized, Open-Label, Parallel-Group, Single-Dose, Multi-Center Study 192
Figure 3 204: Pharmacokinetic and Pharmacodynamic Profile of Insulin Lispro 193
Figure 3 205: Reproducibility of Insulin Action When Administered by Needle-free Jet Injection 193
Figure 3 206: Patient Experiences With Injection Needles 194
Figure 3 207: Inactivated Influenza Via Jet Injection 194
Figure 3 208: Intradermal Rabies Immunization Using NanoJect: A Comparative Study 195
Figure 3 209: Phase 1b, Partial-Blind, Parallel Group, Randomized Study 195
Figure 3 210: A Phase I, Open Label, CT to Evaluate the Safety, Tolerability and Immunogenicity 196
Figure 6 1: Press Release Summary 216

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