TABLE OF CONTENTS I
LIST OF FIGURES XVII
LIST OF CHARTS XXIII
EXECUTIVE SUMMARY 1
EUROPEAN MARKET FOR VASCULAR ACCESS DEVICES AND ACCESSORIES OVERVIEW 1
COMPETITIVE ANALYSIS 3
MARKET TRENDS 5
MARKET DEVELOPMENTS 6
PROCEDURE NUMBERS 7
MARKETS INCLUDED 8
KEY REPORT UPDATES 11
VERSION HISTORY 12
RESEARCH METHODOLOGY 13
1.1 RESEARCH SCOPE 13
1.2 IDATA’S 9-STEP METHODOLOGY 13
Step 1: Project Initiation & Team Selection 13
Step 2: Prepare Data Systems and Perform Secondary Research 15
Step 3: Preparation for Interviews & Questionnaire Design 16
Step 4: Performing Primary Research 17
Step 5: Research Analysis: Establishing Baseline Estimates 19
Step 6: Market Forecast and Analysis 20
Step 7: Identify Strategic Opportunities 22
Step 8: Final Review and Market Release 23
Step 9: Customer Feedback and Market Monitoring 24
DISEASE OVERVIEW 25
2.1 BASIC ANATOMY 25
2.1.1 Human Vascular System 25
2.2 VASCULAR PATHOLOGY AND DISORDERS 26
2.2.1 Cancer 26
2.2.2 End-Stage Renal Disease 27
2.2.3 Diabetes 29
PRODUCT ASSESSMENT 32
3.1 PRODUCT PORTFOLIOS 32
3.1.1 Central Venous Catheters 32
3.1.1.1 Introduction 32
3.1.1.1.1 CVC Procedures 33
3.1.1.1.2 CVC Kits 34
3.1.1.1.3 CVC Market Segments 34
3.1.1.2 AngioDynamics 37
3.1.1.2.1 NeoStar™ 37
3.1.1.3 Centurion Medical Products 37
3.1.1.3.1 Vantex™ 37
3.1.1.3.2 Multi-Med™ 37
3.1.1.3.3 AVA™ 37
3.1.1.4 Cook Medical 37
3.1.1.4.1 Spectrum® 37
3.1.1.5 C.R. Bard 38
3.1.1.5.1 PowerHohn® 38
3.1.1.5.2 Hohn® 38
3.1.1.5.3 Other CVC Offerings 38
3.1.1.6 Medcomp Inc. 38
3.1.1.6.1 Pro-Line® 38
3.1.1.6.2 Vascu-Line® 38
3.1.1.6.3 Other CVC Offerings 38
3.1.1.7 Teleflex Medical 39
3.1.1.7.1 Standard 39
3.1.1.7.2 ARROWg+ard Blue® 39
3.1.1.7.3 ARROWg+ard Blue Plus® 39
3.1.1.7.4 Chlorag+ard® 39
3.2 REGULATORY ISSUES AND RECALLS 40
3.2.1 November 2015 40
3.2.2 October 2015 40
3.2.3 September 2015 41
3.2.4 August 2015 43
3.2.5 July 2015 44
3.2.6 April 2015 46
3.2.7 March 2015 47
3.2.8 February 2015 48
3.2.9 January 2015 48
3.2.10 December 2014 49
3.2.11 October 2014 50
3.2.12 September 2014 51
3.2.13 May 2014 52
3.2.14 April 2014 52
3.2.15 March 2014 53
3.2.16 January 2014 53
3.2.17 December 2013 54
3.2.18 September 2013 55
3.2.19 August 2013 56
3.2.20 June 2013 56
3.2.21 March 2013 57
3.2.22 February 2013 58
3.2.23 December 2012 58
3.2.24 August 2012 58
3.2.25 June 2012 59
3.2.26 May 2012 60
3.2.27 March 2012 61
3.2.28 February 2012 62
3.2.29 January 2012 62
3.3 CLINICAL TRIALS 66
3.3.1 Central Venous Catheters 67
3.4 PRODUCT PIPELINES 82
3.4.1 Alliance Vascular Devices, LLC 82
3.4.1.1 FreeHand Safety Huber Needle® 82
3.4.2 AngioDynamics 82
3.4.2.1 Celerity™ PICC Tip Confirmation System with Navigation 82
3.4.2.2 Firefly 82
3.4.2.3 BioFlo® PICC Line Extension 83
3.4.2.4 BioFlo® Port Line Extension 83
3.4.2.5 Next Generation BioFlo® PICC 83
3.4.2.6 Next Generation BioFlo® Port 83
3.4.3 Bluegrass Vascular Technologies, Inc. 83
3.4.3.1 Surfacer® Inside-Out™ Access System 83
3.4.4 C.R. Bard 83
3.4.4.1 Chemical-Resistant PICCs 83
3.4.4.2 Novel Advanced Material PICCs 84
3.4.4.3 PowerGlide® Pro Midline 84
3.4.4.4 AccuCath® 84
3.4.4.5 Xenesis™ Acute Hemodialysis Catheter 84
3.4.4.6 Site~Rite® 8 Ultrasound System 84
3.4.5 M. C. Johnson 84
3.4.5.1 PICC Securement Device 84
3.4.6 Nipro Medical 85
3.4.6.1 Shielding Safety Needle 85
3.4.6.2 Safety Syringe 85
3.4.6.3 Safety PIVC 85
3.4.7 Parasol Medical 85
3.4.7.1 Catheter Securement Device 85
3.4.8 PAVmed Inc. 85
3.4.8.1 NextCath™ 85
3.4.9 Phase One Medical 85
3.4.9.1 Goldilocks™ Long Term Hemodialysis Catheter 85
3.4.9.2 Triple-Lumen Symetrex™ Hemodialysis Catheter 86
3.4.10 Prodigy Diabetes Care, LLC. 86
3.4.10.1 Insulin Pen Needles 86
3.4.11 Sharklet Technologies, Inc. 86
3.4.11.1 Sharklet™ Central Venous Catheter 86
3.4.12 Starboard Medical 86
3.4.12.1 Catheter Securement Devices 86
3.4.13 Teleflex Medical 87
3.4.13.1 Arrow® Endurance™ Extended Dwell Peripheral Catheter System 87
3.4.13.2 Tip Confirmation for CVCs, Chronic Hemodialysis Catheters & Ports 87
3.4.14 Vascular Access Technologies, Inc. 87
3.4.14.1 SAFECVAD™ 87
COUNTRY PROFILES 88
4.1 INTRODUCTION 88
4.1.1 Population 88
4.1.2 GDP Per Capita 88
4.1.3 Price Index 88
4.2 GERMANY 89
4.3 FRANCE 90
4.4 UNITED KINGDOM 91
4.5 ITALY 92
4.6 SPAIN 93
4.7 BENELUX 94
4.8 SCANDINAVIA 95
4.9 AUSTRIA 96
4.10 SWITZERLAND 97
4.11 PORTUGAL 98
CENTRAL VENOUS CATHETER MARKET 99
5.1 INTRODUCTION 99
5.1.1 CVC Procedures 100
5.1.2 CVC Kits 100
5.1.3 CVC Market Segments 101
5.1.4 Antimicrobial CVCs 101
5.1.5 Multi-Lumen CVCs 102
5.1.6 Chronic CVCs 102
5.2 UNIT ANALYSIS 104
5.2.1.1 Acute CVC Units Sold by Patient Type 104
5.3 MARKET OVERVIEW 105
5.4 MARKET ANALYSIS AND FORECAST 109
5.4.1 Total Central Venous Catheter Market 109
5.4.2 Total Acute Central Venous Catheter Market 117
5.4.2.1 Conventional Acute Central Venous Catheter Market 125
5.4.2.2 Antimicrobial Acute Central Venous Catheter Market 132
5.4.3 Chronic Central Venous Catheter Market 139
5.5 DRIVERS AND LIMITERS 147
5.5.1 Market Drivers 147
5.5.2 Market Limiters 148
5.6 COMPETITIVE MARKET SHARE ANALYSIS 150
ABBREVIATIONS 157
APPENDIX: COMPANY PRESS RELEASES 159

Chart 1 1: Vascular Access Device and Accessories Market by Segment, Europe, 2013 – 2023 2
Chart 1 2: Vascular Access Device and Accessories Market Overview, Europe, 2016 & 2023 2
Chart 3 1: Central Venous Catheter Market Segments, 2015 34
Chart 4 1: Country Profile, Germany, 2016 89
Chart 4 2: Country Profile, France, 2016 90
Chart 4 3: Country Profile, United Kingdom, 2016 91
Chart 4 4: Country Profile, Italy, 2016 92
Chart 4 5: Country Profile, Spain, 2016 93
Chart 4 6: Country Profile, Benelux, 2016 94
Chart 4 7: Country Profile, Scandinavia, 2016 95
Chart 4 8: Country Profile, Austria, 2016 96
Chart 4 9: Country Profile, Switzerland, 2016 97
Chart 4 10: Country Profile, Portugal, 2016 98
Chart 5 1: Central Venous Catheter Market by Segment, Europe, 2013 – 2023 107
Chart 5 2: Central Venous Catheter Market Breakdown, Europe, 2016 108
Chart 5 3: Central Venous Catheter Market Breakdown, Europe, 2023 108
Chart 5 4: Total Central Venous Catheter Market, Europe, 2013 – 2023 111
Chart 5 5: Total Acute Central Venous Catheter Market, Europe, 2013 – 2023 119
Chart 5 6: Chronic Central Venous Catheter Market, Europe, 2013 – 2023 141
Chart 5 7: Leading Competitors, Total Central Venous Catheter Market, Europe, 2016 154

Figure 1 1: Vascular Access Device and Accessories Competitor Market Share Ranking by Segment, Europe, 2016 (1 of 2) 3
Figure 1 2: Vascular Access Device and Accessories Competitor Market Share Ranking by Segment, Europe, 2016 (2 of 2) 3
Figure 1 3: Companies Researched in this Report, Europe, 2016 4
Figure 1 4: Factors Impacting the Vascular Access Device and Accessories Market by Segment, Europe, 2016 5
Figure 1 5: Recent Events in the Vascular Access Device and Accessories Market, Europe, 2013 – 2016 6
Figure 1 6: Vascular Access Procedures Covered, Europe, 2016 7
Figure 1 7: Vascular Access Device and Accessories Markets Covered, Europe, 2016 (1 of 3) 8
Figure 1 8: Vascular Access Device and Accessories Markets Covered, Europe, 2016 (2 of 3) 9
Figure 1 9: Vascular Access Device and Accessories Markets Covered, Europe, 2016 (3 of 3) 10
Figure 1 10: Key Report Updates 11
Figure 1 11: Version History 12
Figure 3 1: Class 2 Device Recall Medtronic 40
Figure 3 2: Class 2 Device Recall Smiths Medical 40
Figure 3 3: Class 2 Device Recall Arrow 41
Figure 3 4: Class 2 Device Recall Arrow 41
Figure 3 5: Class 2 Device Recall Covidien (Medtronic) 42
Figure 3 6: Class 2 Device Recall Arrow 43
Figure 3 7: Class 2 Device Recall Medline 43
Figure 3 8: Class 2 Device Recall Arrow 43
Figure 3 9: Class 2 Device Recall B. Braun 43
Figure 3 10: Class 3 Device Recall Bard Access 44
Figure 3 11: Class 2 Device Recall Covidien (Medtronic) 44
Figure 3 12: Class 2 Device Recall Bard Access 46
Figure 3 13: Class 2 Device Recall Bard Access 46
Figure 3 14: Class 2 Device Recall Medcomp & AngioDynamics 47
Figure 3 15: Class 2 Device Recall Bard Access 47
Figure 3 16: Class 2 Device Recall Arrow 48
Figure 3 17: Class 2 Device Recall Medcomp 48
Figure 3 18: Class 2 Device Recall Arrow 48
Figure 3 19: Class 2 Device Recall Arrow 49
Figure 3 20: Class 2 Device Recall Smiths Medical 49
Figure 3 21: Class 2 Device Recall PFM Medical 49
Figure 3 22: Class 2 Device Recall PFM Medical 49
Figure 3 23: Class 2 Device Recall Becton Dickinson 50
Figure 3 24: Class 2 Device Recall Arrow 50
Figure 3 25: Class 2 Device Recall Arrow 50
Figure 3 26: Class 2 Device Recall Navilyst Medical 50
Figure 3 27: Class 2 Device Recall Argon Medical 51
Figure 3 28: Class 2 Device Recall Arrow 52
Figure 3 29: Class 2 Device Recall Arrow 52
Figure 3 30: Class 2 Device Recall Arrow 53
Figure 3 31: Class 2 Device Recall Bard Access 53
Figure 3 32: Class 2 Device Recall Navilyst Medical 53
Figure 3 33: Class 2 Device Recall Bard Access 54
Figure 3 34: Class 2 Device Recall Smiths Medical 54
Figure 3 35: Class 2 Device Recall B. Braun 54
Figure 3 36: Class 2 Device Recall Smiths Medical 55
Figure 3 37: Class 2 Device Recall Access Scientific 55
Figure 3 38: Class 2 Device Recall Covidien (Medtronic) 55
Figure 3 39: Class 2 Device Recall Arrow 56
Figure 3 40: Class 2 Device Recall Bard Access 56
Figure 3 41: Class 2 Device Recall Becton Dickinson 56
Figure 3 42: Class 2 Device Recall Churchill Medical Systems, Inc. A Vygon Company 57
Figure 3 43: Class 2 Device Recall Bard Access 57
Figure 3 44: Class 2 Device Recall Churchill Medical Systems, Inc. A Vygon Company 57
Figure 3 45: Class 2 Device Recall Medcomp 58
Figure 3 46: Class 2 Device Recall Becton Dickinson 58
Figure 3 47: Class 3 Device Recall Bard Access 58
Figure 3 48: Class 2 Device Recall Medcomp 59
Figure 3 49: Class 1 Device Recall Arrow 59
Figure 3 50: Class 2 Device Recall Arrow 59
Figure 3 51: Class 2 Device Recall Vygon 59
Figure 3 52: Class 2 Device Recall Covidien (Medtronic) 60
Figure 3 53: Class 2 Device Recall Medcomp 61
Figure 3 54: Class 2 Device Recall Churchill Medical Systems, Inc. A Vygon Company 61
Figure 3 55: Class 2 Device Recall Christie Medical Holdings 61
Figure 3 56: Class 3 Recall Bard Access 61
Figure 3 57: Class 2 Device Recall AngioDynamics 62
Figure 3 58: Class 2 Device Recall Becton Dickinson 62
Figure 3 59: Class 2 Device Recall AngioDynamics 62
Figure 3 60: Class 2 Device Recall AngioDynamics 64
Figure 3 61: Class 3 Device Recall AngioDynamics 65
Figure 3 62: Class 2 Device Recall AngioDynamics 65
Figure 3 63: Central Line Placement Study 67
Figure 3 64: The Effects of Anti-infective Central Venous Catheter (CVC) 67
Figure 3 65: The Use of Point of Care Ultra Sound 68
Figure 3 66: Complications Associated With Central Venous Access 68
Figure 3 67: Impact of Ultrasound Guided Central Venous Catheterization 69
Figure 3 68: Randomized, Prospective, Single-center Study 69
Figure 3 69: Remifentanil and Local Anesthesia 70
Figure 3 70: Dissemination of a Simulation-based Mastery Learning Curriculum 70
Figure 3 71: Incidence of Complication 71
Figure 3 72: Comparison of Two Needle Insertion Techniques 71
Figure 3 73: A Monocenter Prospective Study 72
Figure 3 74: A Prospective Study to Compare Point of Care Echocardiography Versus Chest Radiography 72
Figure 3 75: Long-versus Short-Axis Ultrasound Guidance for Subclavian Vein Cannulation 73
Figure 3 76: Use of Chlorhexidine-gel-Impregnated Dressing Compared to Transparent Polyurethane Film Dressing 73
Figure 3 77: Vascular Access in Hematological Patients 74
Figure 3 78: Developing and Maintaining a Central Venous Catheter Registry 74
Figure 3 79: Reliability of Central Venous Pressure Measurements 74
Figure 3 80: SUBclavian Central Venous Catheters Guidance and Examination by UltraSound 74
Figure 3 81: Chlorhexidine Containing IV-securement Dressings 75
Figure 3 82: Comparison of Effectiveness and Safety of Two Methods for Installing Femoral Central Venous Catheters 76
Figure 3 83: A Phase III Study of Peripherally Inserted Versus Centrally Inserted Central Venous Catheters 76
Figure 3 84: Ultrasound Guided Diagnosis of Central Venous Catheters in Children 77
Figure 3 85: Real-time Ultrasound-guided Catheterization of the Axillary Vein in the Intensive Care Unit 77
Figure 3 86: Determination of Anatomic Variations of the Internal Jugular and Femoral Veins 78
Figure 3 87: Comparison of Subclavian, Femoral and Internal Jugular Venous Catheterization 78
Figure 3 88: Landmark vs. Ultrasound Guided Subclavian Central Venous Catheter Placement 79
Figure 3 89: Interest of Ultrasound Coupled to a Guidance System (GPS) 79
Figure 3 90: Risk of Central Venous Stenosis in Patients With Chronic Renal Failure After IJ Line Placement 80
Figure 3 91: Comparison of the Central Venous Catheter Insertion Techniques 80
Figure 3 92: A Multicenter, Open-label, Randomised, Clinical Trial 81
Figure 5 1: Acute CVC Units Sold by Patient Type, Europe, 2016 104
Figure 5 2: Central Venous Catheter Market by Segment, Europe, 2013 – 2023 (€M) 106
Figure 5 3: Central Venous Catheter Market by Segment, Europe, 2013 – 2023 (US$M) 106
Figure 5 4: Total Central Venous Catheter Market, Europe, 2013 – 2023 (€ and US$) 110
Figure 5 5: Units Sold by Country, Total Central Venous Catheter Market, Europe, 2013 – 2023 112
Figure 5 6: Average Selling Price by Country, Total Central Venous Catheter Market, Europe, 2013 – 2023 (€) 113
Figure 5 7: Average Selling Price by Country, Total Central Venous Catheter Market, Europe, 2013 – 2023 (US$) 114
Figure 5 8: Market Value by Country, Total Central Venous Catheter Market, Europe, 2013 – 2023 (€M) 115
Figure 5 9: Market Value by Country, Total Central Venous Catheter Market, Europe, 2013 – 2023 (US$M) 116
Figure 5 10: Total Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€ and US$) 118
Figure 5 11: Units Sold by Country, Total Acute Central Venous Catheter Market, Europe, 2013 – 2023 120
Figure 5 12: Average Selling Price by Country, Total Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€) 121
Figure 5 13: Average Selling Price by Country, Total Acute Central Venous Catheter Market, Europe, 2013 – 2023 (US$) 122
Figure 5 14: Market Value by Country, Total Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€M) 123
Figure 5 15: Market Value by Country, Total Acute Central Venous Catheter Market, Europe, 2013 – 2023 (US$M) 124
Figure 5 16: Conventional Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€ and US$) 126
Figure 5 17: Units Sold by Country, Conventional Acute Central Venous Catheter Market, Europe, 2013 – 2023 127
Figure 5 18: Average Selling Price by Country, Conventional Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€) 128
Figure 5 19: Average Selling Price by Country, Conventional Acute Central Venous Catheter Market, Europe, 2013 – 2023 (US$) 129
Figure 5 20: Market Value by Country, Conventional Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€M) 130
Figure 5 21: Market Value by Country, Conventional Acute Central Venous Catheter Market, Europe, 2013 – 2023 (US$M) 131
Figure 5 22: Antimicrobial Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€ and US$) 133
Figure 5 23: Units Sold by Country, Antimicrobial Acute Central Venous Catheter Market, Europe, 2013 – 2023 134
Figure 5 24: Average Selling Price by Country, Antimicrobial Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€) 135
Figure 5 25: Average Selling Price by Country, Antimicrobial Acute Central Venous Catheter Market, Europe, 2013 – 2023 (US$) 136
Figure 5 26: Market Value by Country, Antimicrobial Acute Central Venous Catheter Market, Europe, 2013 – 2023 (€M) 137
Figure 5 27: Market Value by Country, Antimicrobial Acute Central Venous Catheter Market, Europe, 2013 – 2023 (US$M) 138
Figure 5 28: Chronic Central Venous Catheter Market, Europe, 2013 – 2023 (€ and US$) 140
Figure 5 29: Units Sold by Country, Chronic Central Venous Catheter Market, Europe, 2013 – 2023 142
Figure 5 30: Average Selling Price by Country, Chronic Central Venous Catheter Market, Europe, 2013 – 2023 (€) 143
Figure 5 31: Average Selling Price by Country, Chronic Central Venous Catheter Market, Europe, 2013 – 2023 (US$) 144
Figure 5 32: Market Value by Country, Chronic Central Venous Catheter Market, Europe, 2013 – 2023 (€M) 145
Figure 5 33: Market Value by Country, Chronic Central Venous Catheter Market, Europe, 2013 – 2023 (US$M) 146
Figure 5 34: Drivers and Limiters, Central Venous Catheter Market, Europe, 2016 149
Figure 5 35: Leading Competitors by Country, Total Central Venous Catheter Market, Europe, 2016 153
Figure 5 36: Leading Competitors by Country, Acute Central Venous Catheter Market, Europe, 2016 155
Figure 5 37: Leading Competitors by Country, Chronic Central Venous Catheter Market, Europe, 2016 156
Figure 7 1: Press Release Summary 159

3DT Holdings LLC
3M
Access Scientific
Ambu Inc.
AngioDynamics
Artsana
B. Braun
Baxter International
Becton Dickinson
Bionic
C. R. Bard
Cardinal Health
CareFusion
Codan
Cook Medical
Covidien
Deltamed
Districlass Medical
Edwards Lifesciences
Endeavor Capital
Fresenius
Grupo Sendal
Interrad Medical
Investindustrial
Ivera Medical Corporation
Joline
Kimal
LPI
Medcomp
Medikit
Medtronic
Navilyst Medical
Nipro Medical
Nostix, LLC
Novico
Pentaferte
Perouse Medical
PFM Medical
PFM Medical
PositiveID Corp.
Rays
Romedex
Roundtable Healthcare
Safety Syringes Inc.
Semprus BioSciences
Smiths Medical
SonoSite, Inc.
Teleflex Medical
Terumo
Troge
Vascular Pathways, Inc.
VeriTeQ Acquisition Corp.
VigMed
V-Tech
Vygon