Black Swan Analysis Epiomic™ Epidemiology Series Forecast Report on Type 1 Diabetes Mellitus in 12 Major Markets
Type 1 Diabetes Mellitus (T1DM) is a multisystem disease that progressively destroys the pancreas' ability to produce insulin. This leads to a chronic condition of defective metabolism of fat, carbohydrates and proteins due to the lack of insulin. It occurs mainly in childhood and adolescents, however a rising number of latent autoimmune diabetes of adulthood (LADA) cases have been reported mainly due to a better understanding and diagnosis of the disease.
This report provides the current prevalent population for Type 1 Diabetes Mellitus across 12 Major Markets (USA, Canada, France, Germany, Italy, Spain, UK, Brazil, Japan, India, China and Russia) split by gender and 5-year age cohort. Along with the current prevalence, the report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity.
Providing a value-added level of insight from the analysis team at Black Swan, several of the main symptoms and co-morbidities of Type 1 Diabetes Mellitus have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.
There are many co-morbidities associated with Type 1 Diabetes Mellitus, including:
• Chronic pancreatitis
• Cystic fibrosis
• Autoimmune disorders
• Hyperglycaemia
• Heart and blood vessel diseases (MI, Stroke, Atherosclerosis, Hypertension, Angina)
• Neuropathy
• Nephropathy (leading to CKD)
• Ulcerations
• Eye damage (retinopathy)
• Foot damage
• Ketoacidosis
• Lower limb amputation
• Skin/Mouth conditions
• Pregnancy complications
This report is built using data and information sourced from the proprietary Epiomic patient segmentation database. To generate accurate patient population estimates, the Epiomic database utilises a combination of several world class sources that deliver the most up to date information form patient registries, clinical trials and epidemiology studies. All of the sources used to generate the data and analysis have been identified in the report.
Reason to buy
• Able to quantify patient populations in global Type 1 Diabetes Mellitus market to target the development of future products, pricing strategies and launch plans.
• Gain further insight into the prevalence of the subdivided types of Type 1 Diabetes Mellitus and identify patient segments with high potential.
• Delivery of more accurate information for clinical trials in study sizing and realistic patient recruitment for various countries.
• Provide a level of understanding on the impact from specific co-morbid conditions on Type 1 Diabetes Mellitus prevalent population.
• Identify sub-populations within Type 1 Diabetes Mellitus which require treatment.
• Gain an understanding of the specific markets that have the largest number of Type 1 Diabetes Mellitus patients.
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Table of Contents
• List of Tables and Figures
• Introduction
• Cause of the Disease
• Risk Factors & Prevention
• Diagnosis of the Disease
• Variation by Geography/Ethnicity
• Disease Prognosis & Clinical Course
• Key Comorbid Conditions/Features associated with the disease
• Methodology for quantification of patient numbers
• Top-line Prevalence for Type 1 Diabetes Mellitus
• Features of Type 1 Diabetes Mellitus Patients
o Comorbidities and Sequelae in T1DM Patients
o T1DM patients with Retinopathy
o Prevalence of T1DM defining antibodies
• Abbreviations used in the report
• Other Black Swan Analysis Publications
• Black Swan Analysis Online Patient-Based Databases
• Patient-Based Offering
• Online Pricing Data and Platforms
• References
• Appendix
List of Tables
• Prevalence of Type 1 Diabetes Mellitus, total (000s)
• Prevalence of Type 1 Diabetes Mellitus, males (000s)
• Prevalence of Type 1 Diabetes Mellitus, females (000s)
• T1DM patients by severity of Ketoacidosis, total (000s)
• T1DM patients by kidney function, total (000s)
• T1DM patients with Hypertension, total (000s)
• Incidence of Lower Limb Amputations in T1DM patients, total (000s)
• Incidence of Myocardial Infarction in T1DM patients, total (000s)
• Incidence of Stroke in T1DM patients, total (000s)
• Incidence of Angina in T1DM patients, total (000s)
• T1DM patients with Peripheral Neuropathy, total (000s)
• T1DM patients Diabetic Skin Conditions, total (000s)
• T1DM patients Elevated HbA1c(>7.5%), total (000s)
• T1DM patients with Coeliac Disease, total (000s)
• T1DM patients with Retinopathy, total (000s)
• T1DM patients with Retinopathy by Severity, total (000s)
• T1DM patients with GADA antibodies, total (000s)
• T1DM patients with ICA antibodies, total (000s)
• T1DM patients with IA-2A antibodies, total (000s)
• T1DM patients with IA-2βA antibodies, total (000s)
• Abbreviations and Acronyms used in the report
• USA Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• USA Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• Canada Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• Canada Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• France Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• France Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• Germany Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• Germany Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• Italy Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• Italy Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• Spain Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• Spain Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• UK Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• UK Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• Brazil Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• Brazil Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• Japan Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• Japan Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• India Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• India Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• China Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• China Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
• Russia Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, males (000s)
• Russia Prevalence of Type 1 Diabetes Mellitus by 5-yr age cohort, females (000s)
